Accrual, Enrollment and Screening Site Hubs

Locations

Hawaii | Northern California | Rocky Mountain | Great Plains | Midwest | South |  DoD Center of Excellence | Veterans Affairs

For general inquiries, please contact: CSRNComms@fredhutch.org

I-SCREEN: Improving Strategies for Cancer Reduction through Early-Detection and Engagement

Hawaii, Denver Metro, and Eastern Plains Colorado area

Contact us:

• Kaiser Permanente Colorado: I-Screen-Colorado@kp.org
• Contact information to be updated soon for Kaiser Permanente Hawaii and University of Colorado Cancer Center

The I-SCREEN (Improving Strategies for Cancer Reduction through Early-detection and ENgagement) ACCESS Hub is a collaboration between the University of Colorado Cancer Center, the UCCC Colorado Cancer Screening Program (CCSP), and the Kaiser Permanente regions of Colorado and Hawaii. The I-SCREEN Hub is comprised of diverse health systems with a variety of care delivery models that serve populations that are under-represented in clinical trials and that tend to have low cancer screening utilization, including Hispanics, Asian Americans, Native Hawaiian and Pacific Islanders (NH/PIs), and rural populations. Together, the partners in I-SCREEN have strong track records of active participation and successful recruitment in multi-site cancer research consortia and have the infrastructure necessary to make I-SCREEN an ideal ACCESS Hub for recruiting diverse participants. Health systems and clinics in I-SCREEN serve individuals via Medicare, Medicaid, commercial, and self-pay and/or individual (ACA-based) exchange insurance plans, as well as uninsured and under-insured individuals, and each is a prominent provider of care within the communities that they serve. Therefore, even if individuals change employment, or age into Medicare, the respective health system or clinic remains a coverage and/or care option—including for cancer surveillance and follow-up. As a result, expected 5-year retention is high, and based on prior experience should exceed 65% for individuals ages 55 years and older and approach 80% for patients diagnosed with cancer.

Kaiser Permanente Northern California

PARTICIPATING KAISER PERMANENTE NORTHERN CALIFORNIA MEDICAL FACILITIES

Contact us: VanguardStudyKPNC@kp.org

Kaiser Permanente (KP) will recruit approximately 2,000 eligible participants across diverse medical centers in Northern California. The KP ACCESS Hub will be led by a multidisciplinary team that has decades of expertise in cancer screening and with recruiting participants for large-volume trials.

OK TRUST: Oklahoma Tribal, Rural, Urban Cancer Screening Trial ACCESS Hub 

Oklahoma area

Contact us: oktrust@ou.edu

Through OU Health Stephenson Cancer Center (SCC), the NCI Cancer Screening Research Network (CSRN) will offer screening clinical trials to individuals living in tribal, rural, and inner-city urban locations across Oklahoma. The effort is called the Oklahoma Tribal, Rural, Urban Cancer Screening Trial (OK TRUST) Access Hub. One-third of Oklahomans live in rural counties, and most tribal health care systems are in rural areas. To increase rural access to cancer screening clinical trials, OK TRUST is partnering with rural federally qualified health centers, which are a critical safety net for people without insurance, as well as with tribal nations that operate clinics in rural locations. Together, the entities serve patients from large swathes of rural eastern, southern, and western Oklahoma, where cancer rates are high. Many persons living in urban areas also have trouble accessing cancer screening. OK TRUST is partnering with urban federally qualified health centers in Oklahoma City serving low-income patients who lack health insurance coverage and people who are Black/African American or Spanish-speaking. Other urban partners include OU Health Clinics in Oklahoma City and Tulsa, as well as an urban American Indian health care facility. The participation of OK TRUST in the NCI CSRN will enable Oklahomans to be a vital part of a national, collaborative effort addressing cancer prevention.

Henry Ford Health and Michigan State University Health Sciences Center

Metropolitan Detroit and Mid-Michigan area

Contact us: VanguardStudy@hfhs.org | (313) 874-4969

Henry Ford Health + Michigan State University Health Sciences Center (HFH-MSU), as part of the NCI Cancer Screening Research Network, will recruit diverse patients including African Americans and Arab Americans that are served by the Henry Ford Medical Group and Physician Network in the Metropolitan Detroit and Mid-Michigan areas. HFH has five hospitals and over 50 ambulatory health clinics throughout the region and provides standard of care cancer screening to over 250,000 adults, annually. HFH-MSU also includes over 150 population and basic scientists working to reduce the burden of cancer in our diverse population.

Building Equity in Cancer Screening through Research: The Siteman Catchment CSRN Hub

across Missouri and southern Illinois area

Contact us: SitemanCSRN@wustl.edu

Communities with elevated cancer burden, combined with medically underserved and economic disadvantage, are in critical need of new strategies for early detection of cancer and need to be included in studies testing and implementing emerging technologies, such as those in the CSRN. The CSRN Hub at Siteman Cancer Center and Washington University in St. Louis builds on our institutional infrastructure and our experience in recruiting diverse and under-represented adults into cancer screening trials, including those who live in rural and medically underserved areas without easy access to academic medical centers, those from diverse racial and ethnic backgrounds, and people with varying socioeconomic resources.  Through partnerships with health care systems across Missouri and southern Illinois and robust, ongoing, and iterative engagement with community members, we continue to have a sharp focus on equity so that the promise of cancer screening trials through the CSRN can be realized without exacerbating cancer health disparities. Our goal is to collaborate with partners and community members to reduce the burden of cancer in our communities and improve health outcomes for everyone.

NC Hub

North Carolina area

Contact us: LCCC_VanguardStudy@med.unc.edu

The NC Hub consists of clinics within the UNC Health network and selected FQHC’s that provide a large and diverse patient population with distinctive characteristics and strengths that will support CSRN Vanguard study and other clinical studies of novel screening technologies.

Virginia Cancer Screening Research Network

Virginia area

Contact us:

• virginiacsrn@vcu.edu | (804) 827-2762 | https://www.virginiacsrn.org/
• Saville_Research@inova.org | (571) 472-3517
• research@sentara.com | (833) 866-7766

As part of this NCI National Cancer Screening Research Network, the Virginia Cancer Screening Research Network is a partnership between the Virginia Commonwealth University Massey Comprehensive Cancer Center and the Wright Regional Center for Clinical and Translational Research with VCU Health; the Inova Schar Cancer Institute and its Saville Cancer Screening and Prevention Center; and Sentara Health, the Sentara Health Research Center and academic partner Eastern Virginia Medical School (EVMS).

Murtha Cancer Center Research Program on behalf of the Department of Defense's ACCESS Hub

nine participating Murtha Research Network DoD hospital sites across the us

Contact us: kristen.natale.ctr@usuhs.edu

Murtha Cancer Center Research Program (MCCRP) at Uniformed Services University (USU) is the hub for the federal Biden Cancer Moonshot activities within DoD and we are proud to be utilizing our extensive cancer research network to be able to enroll military, veteran, and beneficiary populations in these important cancer research studies. As part of this effort, MCCRP/USU will represent the DoD as an ACCESS Hub for the NCI National Cancer Screening Research Network. MCCRP/USU plans to open the Vanguard study at all nine of its participating Murtha Research Network DoD Military Treatment Facilities (MTFs).

The U.S. Department of Veterans Affairs

twelve participating sites, affiliated medical centers, and community clinics across the us

Contact us: VHA.CSRN.ACCESSHub@va.gov

The U.S. Department of Veterans Affairs (VA) National Oncology Program and Office of Research and Development through the Cooperative Studies Program Coordinating Center (CSPCC) in Boston will establish a VA ACCESS Hub to enroll Veterans into CSRN trials. The Boston CSPCC is home of the Point of Care Program, an initiative aimed at leveraging VA informatics infrastructure and clinical consortia to conduct clinical trials and is uniquely positioned to support the Hub and supplement the VA lead investigators in the conduct of the CSRN trials. The VA ACCESS Hub will leverage its sites from the NCI and VA Interagency Group to Accelerate Trials Enrollment (NAVIGATE) program to recruit Veterans enrolled in VA care from across the country into CSRN initiatives, starting with the Vanguard trial.