Mazyar Shadman, MD, MPH

/content/dam/www/provider-photos/s/mazyar-shadman/provider-mazyar-shadman-directory-1x.jpg
/content/dam/www/provider-photos/s/mazyar-shadman/provider-mazyar-shadman-directory-2x.jpg
Shadman
Mazyar Shadman, MD, MPH

Mazyar Shadman, MD, MPH

  • Medical Director, Bezos Family Immunotherapy Clinic, Fred Hutch
  • Associate Professor, Clinical Research Division, Fred Hutch
  • Innovators Network Endowed Chair, Fred Hutch
  • Associate Professor, Division of Hematology and Oncology, University of Washington School of Medicine

Medical Oncology

Request an Appointment  Print

“Your positive attitude and willingness to fight have always inspired me.”

— Dr. Shadman

What do you enjoy about being an academic physician?

Every day, I get to integrate science with the art of human interaction. Seeing patients benefit from medical advances, and being active in pushing the science forward, is extremely rewarding. It’s an exciting time for both cancer care and research. We now have access to a variety of novel therapies that enable us to target cancer cells more specifically without causing major side effects. In my field, we’re always looking for a “cure,” but in the meantime, I’m hopeful that we can relegate cancer to a chronic disease and help patients maintain their desired quality of life.

What is your role in cancer treatment?

A diagnosis of cancer kicks off a torrent of life changes, and in the middle of all this disruption are many important decisions to make about your care. My role is to help you thoroughly understand and weigh your options. At Fred Hutch, you have access to a variety of standard and experimental treatments, from chemotherapy to more novel, targeted approaches that may have fewer side effects. We’ll discuss each option in detail — the potential benefits, the risks and the overall impact on your life and family — so that you can make the best choices for your unique situation.

Provider Background

Area of Clinical Practice
Adult blood and marrow transplantation, cellular immunotherapy, hematologic malignancies

Lymphomas

I am a medical oncologist and stem-cell transplant expert who specializes in treating patients with lymphomas and other blood disorders. My clinical trial work focuses on testing novel agents for the treatment of leukemia and lymphoma, with a particular focus on chronic lymphocytic leukemia (CLL). I also study the clinical outcomes of patients who have already been treated. My goal is to identify patient- or disease-specific characteristics that can help us understand the behavior of a disease and predict its responsiveness to different treatments. One particular area of interest is the epidemiology of hematologic neoplasms (abnormal growth in blood-forming tissue). In 2013, I co-authored a study that found a correlation between certain types of allergies and blood cancers.

Diseases Treated

Chronic Lymphocytic Leukemia

Cutaneous Lymphoma

Diffuse Large B-cell Lymphoma

Follicular Lymphoma

Hodgkin Lymphoma

Low Grade Lymphoma

Lymphoma

MALT Lymphoma

Mantle Cell Lymphoma

Marginal Zone Lymphoma

Non-Hodgkin Lymphoma

Waldenström Macroglobulinemia

Languages

English
Persian

Education, Experience and Certifications

Medical Degree
Tehran University of Medical Sciences

Residency
Cleveland Clinic Foundation, Internal Medicine

Fellowship
University of Washington, Hematology-Oncology

Board Certification
Medical Oncology, 2014; Hematology, 2014; Internal Medicine, 2011, American Board of Internal Medicine

Other
MPH, University of Washington

Stories

All news
Dr. Mazyar Shadman, new medical director of the Bezos Family Immunotherapy Clinic, says immunotherapy services are expanding to meet demand
Dr. Mazyar Shadman, new medical director of the Bezos Family Immunotherapy Clinic, says immunotherapy services are expanding to meet demand Increasing timely access to immunotherapy is a main goal July 19, 2024
Blood cancer experts Drs. Roland Walter and Mazyar Shadman receive endowed chairs
Blood cancer experts Drs. Roland Walter and Mazyar Shadman receive endowed chairs Chairs recognize innovation and contributions to blood cancer research July 12, 2023
SCCA, Fred Hutch, and University of Washington Medicine take the spotlight at the American Society of Hematology’s 63rd annual meeting
SCCA, Fred Hutch, and University of Washington Medicine take the spotlight at the American Society of Hematology’s 63rd annual meeting March 8, 2022

Clinical Trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch physicians. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your physician can decide if a study is right for you. 

Find a Clinical Trial Led by Dr. Shadman

Publications

Many of our Fred Hutch physicians conduct ongoing research to improve standards of patient care. Their work is evaluated by other physicians and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch physician has written. 

View Dr. Shadman's Publications

Your Care Team

 

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes physicians, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like registered dietitians, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders. 

Meet Other Providers

Insurance

Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

More About Insurance