“I did a research year at University of Pennsylvania while they were building their proton therapy facility,” Shepherd explained. “It was incredible to witness the technology evolve. After I finished my residency at Penn several years later, the proton therapy center and technology had advanced so much.”
As a young student, Shepherd gravitated toward math and science. In college she worked on research to determine what makes cancer cells sensitive to radiation. Her mentor at the time encouraged her to see what the clinical side of medicine looked like.
“It was a formative moment. I saw how physicians can make a difference in a patient’s life, how a conversation with a specialist could decrease anxiety,” said Shepherd. “I wanted to be part of that.”
Helping patients through something as stressful and life-altering as cancer made oncology very appealing to Shepherd. She felt it was a perfect fit for her nurturing personality. She especially liked the high-tech aspect of radiation oncology with its constant changes and advancements, and the ability to limit toxicities while treating cancer. She has a particular interest in thymic malignancies, which are rare but uniquely benefit from the heart-sparing capabilities of proton therapy. Shepherd serves on multiple committees in the International Thymic Malignancy Interest Group and chairs the ITMIG International Tumor Board.
After her residency at Penn, Shepherd moved to Memorial Sloan Kettering Cancer Center in New Jersey. She worked as a radiation oncologist with a specialty in thoracic cancers (which occur in the area of the torso protected by the rib cage). She was eager to treat patients using protons and further her research on proton therapy and thoracic malignancies. Later, when the New York Proton Center opened in 2019, she treated thoracic patients there. With her strong interest in protons and her leadership skills, she was very excited when the position for proton therapy medical director opened up at Fred Hutch.
“It was particularly enticing because I would be able to work with one of my greatest mentors from my residency at Penn — Dr. Ramesh Rengan,” said Shepherd. “He has helped me so much during my career. In fact, I know many of the physicians in the department already, which makes the prospect of working with them so great. I know they are genuinely caring individuals. Working in a culture where people take care of each other is very important, especially if you are going to move across the country for the job.”
Shepherd understands the challenges to running a proton therapy facility and is looking forward to helping mitigate issues such as insurance coverage.
“With more and more advancements, it’s really amazing to think of what the future potential is for protons,” she said.
Shepherd will continue to see patients with thoracic cancers while she serves as medical director. Her approach is to learn her patients’ background and their understanding of what they are going through; help to dispel any erroneous preconceived notions about treatment or cancer they may have; and help them understand what the oncology is today and what they can expect.
“Just being able to relieve their anxieties — besides offering the best treatment plan, of course — that is my first priority,” she said.
Having lived all her life on the East Coast, Shepherd and her family are excited to explore all the West Coast has to offer. Her family of five loves traveling and spending time outdoors, which makes the Pacific Northwest all the more attractive to them. Please join Fred Hutch in welcoming Shepherd to the proton facility and be sure to share some of your favorite local places for her to explore.