Lev Silberstein, MD, PhD
Associate Professor
Translational Science and Therapeutics Division, Fred Hutch
Dr. Lev Silberstein studies factors that regulate the behavior of normal and malignant stem cells in the bone marrow. He and his colleagues aim to develop new ways to boost blood cell production in patients with blood disorders, inherited bone marrow failure and those recovering from blood stem cell transplants.
Other Appointments & Affiliations
Attending Hematologist, Fred Hutchinson Cancer CenterAttending Hematologist
Fred Hutchinson Cancer Center
Associate Professor, Division of Hematology and Oncology
University of Washington School of Medicine
Education
PhD, University of Cambridge
MBBS equivalent, King’s College School of Medicine and Dentistry
MD, Novosibirsk Medical Institute
Research Interests
Micro-environmental control of hematopoietic stem/progenitor quiescence
Restoration of hematopoietic stem cell function in bone marrow failure
Development of therapeutic strategies to enhance post-transplant reconstitution
Current Projects
Characterization of novel extrinsic regulators of hematopoietic stem cell/progenitor quiescence
Pharmacological modulation of hematopoietic stem cell quiescence to restore hematopoiesis in myelodysplasia (funded by Leukemia and Lymphoma Society Translational Research Program Award)